Endocrine Abstracts

Objective: The objectives of this study were to determine the prevalence of diagnosed and undiagnosed diabetes mellitus (DM), prediabetes and to evaluate the associated risk factors in the sample of adult Turkish population.Methods: A total of 4000 eligible study subjects aged 20 years or older, chosen by multistage sampling on a field were selected. Of those 3721 subjects (2139 women and 1582 men) participated in the study. The study was performed betwe...

Introduction: The aim of this study was to validate the American Thyroid Association (ATA) risk of recurrence staging system (2009).Methods: Retrospective analysed 300 adult (239 women, 61 men) differentiated thyroid cancer patients followed for a median of 57 months (range 38–97).Results: ATA risk stratification of patients according to the system 54.7% low-risk, 39.7% moderate risk, and 5.7% were in the high risk group. The ...

Background: Adrenal carcinoma is rare endocrine cancer. Survival time is short and primary treatment is surgery.Methods: Four patients with histopathologically diagnosed as adrenal carcinoma between 2007 and 2013 were evaluated retrospectively.Results: Two of the patients were female and others were male. Their ages were 39, 50, 55 and 61 respectively. All the patients were admitted to the hospital with abdominal pain. Tumor diamet...

Background: Triple-X (Trisomy X) is found in approximately 1 per 1000 females. Mental retardation is the most common feature in triple-X females. Women with Triple X usually are fertile, but they sometimes get the menopause earlier than other women. They are not generally phenotypically abnormal. Although reproductive organs, pubertal development, and fertility are normal in most cases. Some are first identified in infertility clinics, others in institutions for the mentally r...

PRL hypersecretion is the most common endocrine abnormality due to hypothalamic–pituitary disorders. PRL is the hormone most commonly secreted in excess by pituitary adenomas. Patients usually present with oligo-amenorrhea, galactorrhea, loss of libido, impotence and infertility. If the tumor extends outside of the sella, visual deficit or other mass effects may be seen.A retrospective study was performed during the period 1999–2008. The diagno...

Background: Acromegaly is a relatively uncommon disorder (40–68 cases per million population) caused by oversecretion of growth hormone by a tumor of the pituitary gland. Excessive growth hormone (GH) and insulin-like growth factor (IGF) I concentrations cause gradual changes in facial and acral appearances as well as in many internal tissues.Medhods: Medical records of patients with acromegaly seen between 2000 and 2008 at our hospital were reviewe...

Background: Among the disorders causing hyperthyroidism thyrotropin-secreting pituitary adenomas (TSH-omas) are extremely rare and account for <2% of all pituitary adenomas. Failure to recognize a TSH-oma may lead to improper therapy attempts and dramatic consequences. We have reported a patient that wrongly had diagnosed and treated as primary hyperthyroidism for fifteen years.Case: A 50 years old woman who was on the treatment of propilhyourasil (1...

Introduction: Deposition of amyloid substance within the thyroid gland causing clinically appearent enlargement of the gland is described as amyloid goiter. Although microscopic deposition of amyloid substance in thyroid gland is common in systemic amyloidosis, occurence of amyloid goiter is rare.Case: A 55 years old male patient, who had been diagnosed with multinodular goiter for 10 years, was admitted to our clinic with complaint of increased swelling...

Background: The most common etiology of hypercalcemia is primary hyperparathyroidism (PHPT). PHPT is a disorder of calcium, phosphorus and bone metabolism secondary to uncontrolled increased parathyroid hormone secretion. PHPT has a variable clinical expression. Symptomatic PHPT is still the predominant form of the disease in many parts of the World, especially in developing countries.Methods: We summarized the clinical presentation, biochemical and radi...

Context: The prevalence of NCAH among Turkish women with hirsutism has not been established so far.Objective: To evaluate the prevalences of 21-hydroxylase (21-OHD) and 11-β hydroxylase deficiencies by ACTH stimulation test among hirsute women.Patients and methods: The study population consisted of 285 premenopousal women, aged 16–46 years (mean: 23.2±0.3). All were hirsute and hyperandrogenic. Androgen secreting tum...